Bioactive Small Molecules
Medchemexpress LLC HY-111360 5mg Medchemexpress, SPL-707 CAS:2195361-33-0 Purity:>98%
Medchemexpress, HY-111360 5mg SPL-707 CAS:2195361-33-0 SPL-707 is an orally active, selective signal peptide peptidase-like 2a (SPPL2a) inhibitor with an IC50 of 77 nM for hSPPL2a. SPL-707 inhibits γ-secretase (IC50=6.1 μM) and SPP (IC50=3.7 μM). SPL-707 has the potential for autoimmune diseases research by targeting B cells and dendritic cells. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Cayman Chemical ANTIBODY ML-334 10mg
An inhibitor of the Nrf2-Keap1 protein-protein interaction; binds to the Keap1 Kelch domain (IC50 = 1 µM) to induce dissociation and nuclear translocation of Nrf2 and activation of the ARE in a cell-based assay (EC50 = 12 µM)
Cayman Chemical ANTIBODY AVE-0991 10mg
A Mas receptor agonist; binds to the Mas receptor in bovine aortic endothelial cell membranes and COS cells (IC50s = 21 and 47.5 nM, respectively); inhibits perivascular inflammation and increases plaque stability in an ApoE-/- mouse model of atherosclerosis at 0.58 µmol/kg per day; inhibits the formation of angiotensin II-induced abdominal aortic aneurysm in ApoE-/- mice
Cayman Chemical VInorelbIntartrate 5mg
An inhibitor of microtubule polymerization that blocks mitosis at the metaphase/anaphase transition, preventing HeLa cell proliferation (IC50 = 1.25 nM)
Medchemexpress LLC MA-0204 25mg | 2095128-17-7 | 25 MG
MA-0204 is a potent, highly selective, orally available peroxisome proliferator-activated receptor delta (PPARδ) modulator supplied for research use. It is characterized by CAS 2095128-17-7, molecular weight 476.49 g/mol, and chemical formula C25H27F3N2O4. The compound is provided at high purity for in vitro and pharmacology studies; it is not for human or veterinary use.
- Potent, selective modulation of PPARδ.
- High purity suitable for research applications.
- Supplied as a solid small-molecule in multiple laboratory pack sizes.
- Appropriate for in vitro pharmacology, SAR, and preclinical studies.
- Not for clinical, human, or veterinary use.
Medchemexpress LLC Flavin adenine dinucleotide | 146-14-5 | 98.9% | 100 MG
Flavin adenine dinucleotide (FAD) is a redox cofactor, specifically a prosthetic group of a protein, involved in several important enzymatic reactions in metabolism. This product is the analytical standard of Flavin adenine dinucleotide and is intended for research and analytical applications.
- Analytical standard of flavin adenine dinucleotide.
- Intended for research and analytical applications.
- Functions as a redox cofactor.
- Involved in important enzymatic reactions in metabolism.
Medchemexpress LLC PD-L1 inhibitory peptide TFA | 1983.29 | 50MG
PD-L1 inhibitory peptide TFA is an inhibitor peptide targeting programmed cell death ligand 1 (PD-L1). It binds to PD-L1, relieving immunosuppression and restoring the antitumor activity of T cells, making it promising for cancer research.
- Targets programmed cell death ligand 1 (PD-L1)
- Relieves immunosuppression
- Restores antitumor activity of T cells
- Promising for cancer research
eMolecules 67869-62-9 | Medchem Express | GPRP | 5mg | 724442467 | HY-P0074 | MFCD00065510 | 425.49 | C18H31N7O5
Medchem Express | GPRP | 5mg | 724442467 | HY-P0074 | 67869-62-9 | MFCD00065510 | 425.490 | C18H31N7O5
Cayman Chemical JWH 398 5CLOronaphhyl Isom 5mg
An analytical reference standard that is structurally similar to known synthetic cannabinoids; intended for research and forensic applications
Cayman Chemical LevobupIvacaIn-d9hydrochlo 5mg
An internal standard for the quantification of levobupivacaine by GC- or LC-MS
Cayman Chemical 9 Z 11 E 13 Z-OctadecatrIe 5mg
A fatty acid methyl ester; isomer of 9(Z),11(E),13(E)-octadecatrienoic acid methyl ester; has been used as a standard for the quantification of 9(Z),11(E),13(Z)-octadecatrienoic acid in wild growing pomegranate seed oil
Medchemexpress LLC Wyrgrl | 1021155-39-4 | 99.9% | 849.98 | 25 MG
WYRGRL is a collagen II-targeting peptide designed to bind specifically to collagen II α1. This short peptide sequence is effective in cartilage targeting and has been shown to significantly enhance the cartilage-targeting efficiency of peptide-functionalized nanoplatforms in vivo.
- Binds to collagen II α1
- Short cartilage-targeting peptide sequence
- Increases cartilage-targeting efficiency for peptide-functionalized nanoplatforms in vivo by approximately 72-fold
- For research use only
- Available in multiple sizes
- Stable under recommended storage conditions
- Appears as a white to off-white solid
Cayman Chemical 3 4MethylendIoxy PyrovalRo 5mg
A metabolite produced during phase I metabolism of 3,4-MDPV
Cayman Chemical OrItavncInphosphate 5mg
A semisynthetic glycopeptide antibiotic that inhibits the growth of Gram-positive bacteria; inhibits the growth of clinical isolates of MRSA, MSSA, VREF, VSRF, and other staphylococci, streptococci, and enterococci (MIC90s = ≤0.008-0.5 mg/L); inhibits growth of S. aureus in a neutropenic-mouse thigh model of infection (ED50 = 0.95 mg/kg for single dose); improves survival of mice in an inhalation model of B. anthracis Ames anthrax
Medchemexpress LLC TFMU-ADPr diammonium | 00-00-0 | 98.8% | 805.5 g/mol | C25H32F3N7O16P2 | 5 MG
TFMU-ADPr diammonium is a fluorescent ADP-ribose-based substrate used to monitor poly(ADP-ribose) glycohydrolase (PARG) activity in biochemical assays. Upon enzymatic cleavage the molecule releases a fluorophore, enabling quantitative measurement of PAR hydrolase activity and facilitating inhibitor screening and enzymology studies.
- Releases fluorescent reporter upon PARG cleavage.
- High purity (98.8%) for reproducible assay results.
- High aqueous solubility (125 mg/mL); may require sonication.
- Solid, white to off-white form for easy handling and storage.
- Stable when stored under recommended conditions (-20°C under nitrogen).